SYRE insider trades & Congress trades
Spyre Therapeutics, Inc.: public insider filings and Congress disclosures, in one place.
Bourse has recorded 34 open-market insider transactions in Spyre Therapeutics, Inc. (SYRE) (0 purchases with code P and 34 sales with code S), the most recent on October 1, 2026.
In the last 90 days: 0 purchases by 0 insiders ($0) and 31 sales by 3 ($12.3M).
Insider transactions
SEC Form 4, open-market purchases (P) and sales (S) only. Awards, option exercises and tax withholding are excluded. “After” shows the stock’s return over the month following the trade, where available.
| Date | Insider | Role | Type | Shares | Price | Value | After 1M |
|---|---|---|---|---|---|---|---|
| Oct 1, 2026 | King-Jones Heidy | See Remarks | Sell | 400 | $89.24 | $36K | +0.0% |
| Oct 1, 2026 | King-Jones Heidy | See Remarks | Sell | 16,605 | $90.35 | $1.50M | +0.0% |
| Oct 1, 2026 | King-Jones Heidy | See Remarks | Sell | 7,228 | $91.35 | $660K | +0.0% |
| Oct 1, 2026 | King-Jones Heidy | See Remarks | Sell | 2,100 | $92.70 | $195K | +0.0% |
| Oct 1, 2026 | King-Jones Heidy | See Remarks | Sell | 2,600 | $93.46 | $243K | +0.0% |
| Oct 1, 2026 | Turtle Cameron | Chief Executive Officer | Sell | 600 | $89.14 | $53K | +0.0% |
| Oct 1, 2026 | Turtle Cameron | Chief Executive Officer | Sell | 2,683 | $90.10 | $242K | +0.0% |
| Oct 1, 2026 | Turtle Cameron | Chief Executive Officer | Sell | 2,638 | $91.49 | $241K | +0.0% |
| Oct 1, 2026 | Turtle Cameron | Chief Executive Officer | Sell | 3,989 | $92.31 | $368K | +0.0% |
| Oct 1, 2026 | Turtle Cameron | Chief Executive Officer | Sell | 4,990 | $93.37 | $466K | +0.0% |
| Oct 1, 2026 | Turtle Cameron | Chief Executive Officer | Sell | 100 | $93.91 | $9K | +0.0% |
| Oct 1, 2026 | Burrows Scott L | Chief Financial Officer | Sell | 600 | $89.07 | $53K | +0.0% |
| Oct 1, 2026 | Burrows Scott L | Chief Financial Officer | Sell | 1,500 | $90.27 | $135K | +0.0% |
| Oct 1, 2026 | Burrows Scott L | Chief Financial Officer | Sell | 2,100 | $91.92 | $193K | +0.0% |
| Oct 1, 2026 | Burrows Scott L | Chief Financial Officer | Sell | 3,071 | $92.95 | $285K | +0.0% |
| Oct 1, 2026 | Burrows Scott L | Chief Financial Officer | Sell | 229 | $93.57 | $21K | +0.0% |
| Sep 30, 2026 | Burrows Scott L | Chief Financial Officer | Sell | 17,500 | $89.89 | $1.57M | +0.0% |
| Sep 2, 2026 | King-Jones Heidy | See Remarks | Sell | 400 | $90.00 | $36K | +0.1% |
| Sep 2, 2026 | Burrows Scott L | Chief Financial Officer | Sell | 18,232 | $89.35 | $1.63M | +0.1% |
| Sep 1, 2026 | Turtle Cameron | Chief Executive Officer | Sell | 2,500 | $86.36 | $216K | +0.1% |
| Sep 1, 2026 | Turtle Cameron | Chief Executive Officer | Sell | 8,400 | $87.15 | $732K | +0.1% |
| Sep 1, 2026 | Turtle Cameron | Chief Executive Officer | Sell | 3,700 | $88.06 | $326K | +0.1% |
| Sep 1, 2026 | Turtle Cameron | Chief Executive Officer | Sell | 400 | $89.07 | $36K | +0.1% |
| Sep 1, 2026 | King-Jones Heidy | See Remarks | Sell | 4,845 | $86.40 | $419K | +0.1% |
| Sep 1, 2026 | King-Jones Heidy | See Remarks | Sell | 16,548 | $87.20 | $1.44M | +0.1% |
| Sep 1, 2026 | King-Jones Heidy | See Remarks | Sell | 6,206 | $88.17 | $547K | +0.1% |
| Sep 1, 2026 | King-Jones Heidy | See Remarks | Sell | 400 | $89.38 | $36K | +0.1% |
| Sep 1, 2026 | Burrows Scott L | Chief Financial Officer | Sell | 900 | $86.25 | $78K | +0.1% |
| Sep 1, 2026 | Burrows Scott L | Chief Financial Officer | Sell | 4,384 | $87.11 | $382K | +0.1% |
| Sep 1, 2026 | Burrows Scott L | Chief Financial Officer | Sell | 2,016 | $88.03 | $177K | +0.1% |
Showing the 30 most recent of 34 transactions.
Data as of November 8, 2026. Public filings only. A purchase or sale by a politician or an insider does not by itself imply any wrongdoing.
New to these filings? Read how to read a Form 4, how Congress trades are disclosed and what insider cluster buying means. Sources and limits are on the Methodology page.
See these filings as they land
Bourse collects Congress trades, SEC Form 4 insider filings and 13F fund holdings in one live feed, and flags insider buying clusters automatically. Free to start.
Bourse provides financial data and editorial information, parts of which are generated by AI. This page is for general education only. It is not personalised investment advice or a recommendation to buy or sell any financial instrument. Make your own decisions.